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Calcium channel blocker overdose (blood pressure medication overdose)

Description Calcium channel blo...


Description

Calcium channel blockers are blood pressure medications. Overdoses can occur accidentally or intentionally. Severe overdoses can result in very low blood pressure, slow heart rates and death. Common drugs in this class are: Amlodipine (Norvasc), Diltiazem (Cardizem, Dilacor), Nifedipine (Adalat, Procardia), Verapamil (Calan, Isoptin, Verelan). Accidental ingestion of even one pill in an infant requires immediate medical attention as it can be serious and even fatal.

Symptoms

Confusion, low blood pressure, slow heart rate, fainting, nausea, weakness, drowsiness, breathing problems, coma, seizure, death.

Tests

Common tests used for diagnosis and treatment

Workup:
A history and physical exam will be performed. Tests are done to identify the organ damage done by the overdose, and to rule out other causes of the symptoms. The diagnosis is made through the history since blood levels may not be readily available.

Tests:
Pregnancy (BHCG) test, Complete blood count (CBC), Comprehensive metabolic panel (CMP), CT Scan, Electrocardiogram (EKG), Troponin, Urinalysis (UA), X-ray

Other Specific Tests: Urine and serum toxicology screen

Specialists:
Medical Toxicology

Treatment

Depending on the severity of symptoms, treatment may include Intravenous fluids, glucagon, glucose, insulin and calcium infusions. Intubation and medications to raise the blood pressure (such as norepinephrine) may be necessary. 

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Mediref: Calcium channel blocker overdose (blood pressure medication overdose)
Calcium channel blocker overdose (blood pressure medication overdose)
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https://mediref.blogspot.com/2021/12/calcium-channel-blocker-overdose-blood.html
https://mediref.blogspot.com/
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