Description A rare inherited di...
Description
A rare inherited disorder that causes hives (urticaria) after exposure to cold. Other symptoms such as fever and joint pain may be prominent. These episodes are triggered by exposure to cold and may last hours to a few days. Familial cold urticaria is also known as familial cold auto-inflammatory syndrome. The first episodes usually occur during infancy and last throughout a person's life.
Symptoms
Rash (hives), fever, itching, and joint pain after exposure to cold.
Tests
Common tests used for diagnosis and treatment
Workup:
A history and physical exam will be performed. Genetic testing may be recommended.
Other Specific Tests: Allergy testing
Specialists:
Internal Medicine, Pediatrics, Family Practice, Allergy and Immunology, Pediatric Allergy and Immunology
Workup:
A history and physical exam will be performed. Genetic testing may be recommended.
Other Specific Tests: Allergy testing
Specialists:
Internal Medicine, Pediatrics, Family Practice, Allergy and Immunology, Pediatric Allergy and Immunology
Treatment
Treatment includes steroids, and antihistamines (such as diphenhydramine/Benadryl) for the itching. When symptoms are significant and not well controlled with antihistamines alone, injectable medications such as anakinra (Kineret) or canakinumab (Ilaris) may be effective.